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Notices |
PRF is grateful to the National Institutes of Health's National Institute of Neurological Disorders and Stroke for providing content used on this site.

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Surgery for PD is currently used in many centers around the world and STN targeting is mostly performed by with the aid of microrecording and microstimulation. The neurophysiological characteristics of the RN in patients with PD appear to be similar to those described for the STN, which could potentially lead to the misinterpretation of the data obtained during surgery and the ensuing misplacement of the DBS electrode. This report may serve to alert surgeons to this possibility. RN= red nucleus STN= subthalamic nucleus
Ever wonder what happens when electrodes shift, migrate or travel upstream like the salmon in the spring? The departments of neuroradiology, neurosurgery and neurology from the University of Navarra in Pamplona, Spain reported recently on what occurs when deep brain stimulation electrodes come to rest in the red nucleus. The surgeons preferred the subthalamic nucleus as the site for deep brain stimulation, but in two incidents they placed electrodes elsewhere. The investigative team described the patient response to the unusual situation. |
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As Parkinson's disease becomes more complex and patients require multiple drugs to counter the symptoms of illness, clinicians frequently request patients keep a journal. The purpose is to note one's physical status as the day unfolds, half hour upon half hour. Though cumbersome and demanding, as one must remember to make notes every thirty minutes, the entries tend to show patterns when compiled into weeks. This data is valuable, especially from the patient who commits to recording the details, because it is not colored by recollection, but is an on- going recording of the effects of medication on physical function. With this information clinicians may be able to optimize a patient's medications to achieve the best possible level of functioning.
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From: An Essay On The Shaking Palsy |
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So slight and nearly imperceptible are the first inroads of this malady, and so extremely slow is its progress, that it rarely happens, that the patient can form any recollection of the precise period of its commencement. The first symptoms perceived are, a slight weakness, with a proneness to trembling in some particular part; sometimes in the head, but most commonly in one of the hands and arms. These symptoms gradually increase in the part first affected; and at an uncertain period, but seldom in less than twelve months or more, the morbid influence is felt in some other part. Thus assuming one of the hands and arms to be first attacked, the other, at this period become similarly affected. After a few months more the patient is found to be less strict than usual in preserving upright posture: this being most observable whist walking, but sometimes whilst sitting or standing. Sometime after the appearence of this symptom, and during its slow increase, one of the legs is discovered to tremble, and is also found to suffer fatigue sooner than the leg of the other side: and in a few months this limb becomes agitated by similar tremblings, and suffers a similar loss of power. |
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From Around the Web |
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Dementia, Memory And ... 'What Was I Saying?' |
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Exercise for Parkinson's: Healthy Life on 5/13/08 |
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Electrode Re-implantation Helps Some Parkinson's Disease Patients |
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Stamp retires to work for noble cause |
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Comforted by 'Life in the Balance,' Thomas Graboys' memoir on Parkinson's and dementia |
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14th Annual Parkinson's Unity Walk Most Successful Event to Date |
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Copyright © 2003-2006 Parkinson Research Foundation, Inc. All rights reserved worldwide.
Site management by CharitableOperations.com.
This national website which is dedicated to Parkinson's disease is also your ultimate resource for information on Parkinson's Research, PD Symptoms, Motor symptoms, Non-Motor Symptoms, Incidence, Related diseases, Parkinson-Plus diseases, Pathology, Pathophysiology, Genetic, Toxins, Head trauma, Treatment, Pharmacological Treatments, Levodopa, Dopamine Agonists, MAO-B Inhibitor, SSRI's and SSNRI's, Surgical Interventions, Nutrients, Physical exercise, Prognosis, References, External links, Eponymous diseases, Geriatrics, Zelapar, Restless Leg Syndrome, and related Neurological disorders. Although many contributions are American and from Canada, the site seeks to support patients, caregivers, doctors and researchers worldwide. We currently maintain a parkinson forum instead of a listserv.
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